Royal Air Force Typhoon FGR4s have joined forces with France's air force in a combined operation on an subterranean weapons facility in Syrian territory operated by the Islamic State group (IS), as stated by the UK Ministry of Defence.
The site, located using intelligence, was believed to be containing munitions and bombs, the release indicated, and was located in mountainous terrain just north of the historic site of Palmyra in central Syria.
"The RAF jets used laser-guided Paveway IV weapons to target a series of entry passages providing entry to the depot... initial indications indicate the target was engaged successfully," the MoD said.
There was no indication of any civilian casualties in the strike conducted Saturday night and each participating jet made a safe return, the defence officials confirmed.
The British jets were supported by a Voyager aerial refuelling aircraft.
Daesh - also known as the so-called Islamic State - imposed extremist governance over large swathes of Iraq and Syria prior to its 2019 collapse.
"This strike demonstrates the UK's leading role, and commitment to work closely with allied nations, to eliminate any revival of Daesh and their harmful and extremist ideologies in the area," Britain's Defence Chief John Healey remarked.
British military aircraft have conducted overwatch operations over Syrian airspace to "prevent any attempted comeback" of the group following its defeat at the Baghuz confrontation in the year 2019, the MoD reported.
"I extend gratitude to the personnel of the UK armed forces involved in this mission for their skill and their bravery," Healey commented. "Including them were numerous British troops on duty over Christmas and New Year. This operation, to eliminate militants who pose a risk to our safety, highlights how UK forces are always on standby, continuously, protecting the UK within its borders and strong abroad."
In December, the American forces conducted what it termed a "large-scale strike" against IS targets in Syria, following an assault claimed the lives of two American soldiers and a local interpreter in Palmyra.
The United Nations reports Islamic State still maintains between 5,000 and 7,000 militants in Syria and Iraq.